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Current Trends and Limitations in Dengue Antiviral Research.
Obi JO, Gutiérrez-Barbosa H, Chua JV, Deredge DJ. Obi JO, et al. Trop Med Infect Dis. 2021 Sep 30;6(4):180. doi: 10.3390/tropicalmed6040180. Trop Med Infect Dis. 2021. PMID: 34698303 Free PMC article. Review.
The BRPF1 bromodomain is a molecular reader of di-acetyllysine.
Obi JO, Lubula MY, Cornilescu G, Henrickson A, McGuire K, Evans CM, Phillips M, Boyson SP, Demeler B, Markley JL, Glass KC. Obi JO, et al. Curr Res Struct Biol. 2020;2:104-115. doi: 10.1016/j.crstbi.2020.05.001. Epub 2020 May 12. Curr Res Struct Biol. 2020. PMID: 33554132 Free PMC article.
The structure of NAD+ consuming protein Acinetobacter baumannii TIR domain shows unique kinetics and conformations.
Klontz E, Obi JO, Wang Y, Glendening G, Carr J, Tsibouris C, Buddula S, Nallar S, Soares AS, Beckett D, Redzic JS, Eisenmesser E, Palm C, Schmidt K, Scudder AH, Obiorah T, Essuman K, Milbrandt J, Diantonio A, Ray K, Snyder MLD, Deredge D, Snyder GA. Klontz E, et al. Among authors: obi jo. J Biol Chem. 2023 Nov;299(11):105290. doi: 10.1016/j.jbc.2023.105290. Epub 2023 Sep 25. J Biol Chem. 2023. PMID: 37758001 Free PMC article.
Characterization of interaction between blood coagulation factor VIII and LRP1 suggests dynamic binding by alternating complex contacts.
Chun H, Kurasawa JH, Olivares P, Marakasova ES, Shestopal SA, Hassink GU, Karnaukhova E, Migliorini M, Obi JO, Smith AK, Wintrode PL, Durai P, Park K, Deredge D, Strickland DK, Sarafanov AG. Chun H, et al. Among authors: obi jo. J Thromb Haemost. 2022 Oct;20(10):2255-2269. doi: 10.1111/jth.15817. Epub 2022 Aug 4. J Thromb Haemost. 2022. PMID: 35810466 Free PMC article.